Fucosyltransferase Inhibitor, 2F-Peracetyl-Fucose A cell-permeable fluorinated fucose derivative that acts as an inhibitor of fucosyltransferases following its uptake and metabolic transformation into a GDP-fucose mimetic. Treatment of HL-60 cells with this inhibitor shows complete abolition of Lewis-X and SLex within 3 days. Also abolishes P-selectin binding and exhibits faster rolling cells on E-selectin and P-selectin coated surfaces. Does not affect cell viability or their doubling time even at 200 µM levels. 产品信息 Form White solid Primary Target Fucosyltransferase Molar mass 292.3 Protect from Light 是的 Packaged under inert gas 是的 Cell permeable 是的 Reversible 是的 Purity ≥98% by NMR Solubility DMSO Chemical formula C12H17FO7 商店和运输信息 Storage -20°C Ship Shipped at Ambient Temperature or with Blue Ice or with Dry Ice Standard Handling