|
Glutathione Reductase Antibody (Clone 2B3)
Monoclonal antibody to detect Glutathione Reductase in human samples.
Product Overview
Product Name: Glutathione Reductase Antibody (Clone 2B3)
Antibody Target: Glutathione Reductase
Alternative Name: GSR, GLUR, GRD1
Host: Mouse
Antibody Type: Monoclonal
Isotype: Mouse IgG1
Immunogen: Recombinant human protein purified from E.coli
Accession#: P00390
Gene ID: 2936
Appearance: Colorless liquid
Concentration: 1 mg/ml
Formulation: 100 µl of antibody in HEPES with 0.15 M NaCl, 0.01 % BSA, 0.03 % sodium azide, and 50 % glycerol
Purification: Ammonium sulphate precipitation
Species Reactivity: Human
Application: IP, ELISA.
Positive Control: WB and IP: HeLa cell lysate
Application & Usage: IP: 1-2 µl, ELISA.
Storage Temp.: -20 °C
Shipping: gel pack
Background Descriptions: Glutathione reductase (GR) is a member of pyridine nucleotide-disulfide oxidoreductases, which includes the closely related enzymes thioredoxin reductase, lipoamide dehydrogenase, trypanothione reductase and mercuric ion reductase. GR is a cytoplasmic flavoenzyme widely distributed in aerobic organisms. The dimeric protein is composed of two identical subunits, each containing 1 FAD and 1 redox-active disulfide/dithiol as components of the catalytic apparatus. It plays a role in maintaining glutathione (GSH) in its reduced form by catalyzing the reduction of glutathione disulfide (GSSG). In most eukaryotic cells, GR maintains the ratio of [GSH]/[GSSG] elevated, and participates in several vital functions such as the detoxification of reactive oxygen species as well as protein and DNA biosynthesis.
Handling: The antibody solution should be gently mixed before use
USAGE: For Research Use Only! Not For Use in Humans. |