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EDEM3 Antibody
Polyclonal antibody to detect EDEM3 in human, mouse and rat samples
Product Overview
Product Name: EDEM3 Antibody
Antibody Target: EDEM3
Alternative Name: Alpha-1, 2-mannosidase EDEM3
Host: Rabbit
Antibody Type: Polyclonal
Isotype: Rabbit IgG
Immunogen: Synthetic peptide at C-terminal (BV-M5)
Accession#: Q9BZQ6
Gene ID: 80267
Appearance: Colorless liquid
Concentration: 0.5 mg/ml
Formulation: 100 µg (0.5 mg/ml) of antibody in PBS, 0.01 % BSA, 0.01 % thimerosal, and 50 % glycerol, pH7.2
Purification: Affinity purified
Species Reactivity: Mouse, rat, human
Application: Western blot
Positive Control: 3T3 cell lysate
Application & Usage: Western blot: 1:200
Storage Temp.: -20 °C
Shipping: gel pack
Background Descriptions: EDEM3 belongs to the glycosyl hydrolase 47 family. It is involved in endoplasmic reticulum-associated degradation (ERAD). Quality control in the endoplasmic reticulum (ER) ensures that only properly folded proteins are retained in the cell through recognition and degradation of misfolded or unassembled proteins. EDEM3 accelerates the degradation of misfolded glycoproteins in the ER. It also accelerates the glycoprotein ERAD by proteasomes and this process depends on mannose-trimming from the N-glycans. It is most likely to have some alpha 1, 2-mannosidase activity.
Handling: The antibody solution should be gently mixed before use
USAGE: For Research Use Only! Not For Use in Humans. |