|
Anti-Rho GTPase-activating protein 27
Description:
Anti-Rho GTPase-activating protein 27 Antibody
Promotional Text:
Special Shipping Offer on Antibodies
100% Performance Guaranteed
Molecular Weight:
~100 kDa observed
Immunogen:
KLH-conjugated linear peptide corresponding to human Rho GTPase-activating protein 27.
Background Information:
Rho GTPase-activating protein 27 is a multidomain cytoplasmic protein belonging to a large family of over 70 Rho-GAP proteins which regulate the activity of Rho GTPases. In general, Rho-GAP proteins enhance the activity of Rho GTPases resulting in more rapid inactivation of Rho GTPases. Rho-GAP proteins have been implicated in many cellular processes such as endocytosis, exocytosis, cytokinesis, cell migration, differentiation, and tumor suppression. Rho GTPase-activating protein 27, has been detected in the spleen, and in various cancer cells, and may play a role in clathrin-mediated endocytosis.
View All »
Species Reactivity:
Mouse
Human
Species Reactivity Note:
Demonstrated to react with Mouse. Predicted to react with Human based on 100% sequence homology. Other homologies: Rat (94% sequence homology.)
Application Notes:
Immunoprecipitation Analysis: A representative lot was used by an independent laboratory in mouse intestine tissue lysate verified by mass spectrometry. (Dr. Tony Pawson, Mount Sinai Hospital Toronto.)
Control:
Mouse skeletal muscle tissue lysate
Quality Assurance:
Evaluated by Western Blot in mouse skeletal muscle tissue lysate.
Western Blot Analysis: 0.5 µg/mL of this antibody detected Rho GTPase-activating protein 27 in 10 µg of mouse skeletal muscle tissue lysate.
Purification Method:
Affinity purified
Presentation:
Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Storage Conditions:
Stable for 1 year at 2-8°C from date of receipt.
UniProt Number:
Q6ZUM4
Entrez Gene Number:
NP_954976
Gene Symbol:
ARHGAP27
CAMGAP1
SH3D20
PP905
Alternate Names:
Rho GTPase-activating protein 27
CIN85-associated multi-domain-containing Rho GTPase-activating protein 1
Rho-type GTPase-activating protein 27
SH3 domain-containing protein 20
Usage Statement:
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
View All »
Key Applications:
Western Blotting
Immunoprecipitation
Product Name:
Anti-Rho GTPase-activating protein 27
Concentration:
Please refer to the Certificate of Analysis for the lot-specific concentration.
Antibody Type:
Polyclonal Antibody
Qty/Pk:
100 μg
Format:
Affinity Purified
Host:
Rabbit |