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Anti-TDRD1
Description:
Anti-TDRD1 Antibody
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Molecular Weight:
~132 kDa observed. Uncharacterized bands appear at ~95 and ~115 kDa in some lysates.
Immunogen:
KLH-conjugated linear peptide corresponding to human TDRD1.
Background Information:
Tudor domain-containing protein 1 (TDRD1) is found exclusively in the testis and ovary. It contains an N-terminal myeloid-nervy-DEAF-1 (MYND) domain and four tudor domains. The tudor domains interact with symmetrical dimethyl arginines in piwi proteins such as MILI. The interaction of TDRD1 with MILI in murine germ cells facilitate the binding of MILI to piRNA molecules, and this may promote the silencing of transposons in germ cells involved in gametogenesis.
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Species Reactivity:
Mouse
Species Reactivity Note:
Demonstrated to react with Mouse. Predicted to react with Human based on immunogen design. Other homologies: Rat (89% sequence homology).
Application Notes:
Immunoprecipitation Analysis: A representative lot was used by independent laboratory in mouse testis tissue lysate. (Dr. Tony Pawson, Mount Sinai Hospital Toronto)
Control:
Mouse testis tissue lysate
Quality Assurance:
Evaluated by Western Blot in mouse testis tissue lysate.
Western Blot Analysis: 0.5 µg/mL of this antibody detected TDRD1 on 10 µg of mouse testis tissue lysate.
Purification Method:
Affinity purified
Presentation:
Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Storage Conditions:
Stable for 1 year at 2-8°C from date of receipt.
UniProt Number:
Q9BXT4
Entrez Gene Number:
NP_942090
Gene Symbol:
TDRD1
Alternate Names:
Tudor domain-containing protein 1
Cancer/testis antigen 41.1
CT41.1
Usage Statement:
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Key Applications:
Western Blotting
Immunoprecipitation
Product Name:
Anti-TDRD1
Concentration:
Please refer to the Certificate of Analysis for the lot-specific concentration.
Antibody Type:
Polyclonal Antibody
Qty/Pk:
100 μg
Format:
Affinity Purified
Host:
Rabbit |