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Ilimaquinone
A cytoplasmic microtubule inhibitor.
Product Overview
Product Name: Ilimaquinone
Alternate Name/Synonyms: 3-[(Decahydro-1α,2β,4aβ-trimethyl-5-methylene-1-naphthyl)methyl]-2-hydroxy-5-methoxybenzoquinone; IQ
Description: Cell-permeable. A marine sponge metabolite that acts as a cytoplasmic microtubule inhibitor. Induces a complete and reversible breakdown/disruption of Golgi membranes into smaller vesicular structures and blocks the association of the ADP-ribosylation factor and β-COP to the Golgi membrane. Ilimaquinone displays anticancer activity via GADD153-mediated pathway.
Peptide Sequence: N/A
Appearance: Yellow solid
Formulation: N/A
CAS Number: 71678-03-0
Molecular Formula: C₂₂H₃₀O₄
Molecular Weight: 358.47
Purity: ≥98% by HPLC
Solubility:DMSO
Storage Temp.: -20°C
Shipping Conditions: gel pack
Handling: Protect from air and light
SMILES: CC1CCC2(C(C1(C)CC3=C(C(=O)C=C(C3=O)OC)O)CCCC2=C)C
InChi: InChI=1S/C22H30O4/c1-13-7-6-8-18-21(13,3)10-9-14(2)22(18,4)12-15-19(24)16(23)11-17(26-5)20(15)25/h11,14,18,24H,1,6-10,12H2,2-5H3/t14-,18+,21+,22+/m0/s1
InChi Key: JJWITJNSXCXULM-YVUMSICPSA-N
PubChem CID: 72291
MDL Number: MFCD00274432
USAGE: For Research Use Only! Not For Use in Humans. |