Spautin-1 An USP10 and USP13 inhibitor Product Overview Product Name: Spautin-1 Alternate Name/Synonyms: 6-Fluoro-N-(4-fluorobenzyl)quinozaline-4-amine Description: Cell-permeable. A specific and potent autophagy inhibitor in mammalian cells. It promotes the degradation of Vps34 PI3 kinase complexes by inhibiting two ubiquitin specific peptidases, USP10 and USP13, that target the Beclin1 subunit of Vps34 complexes. Spautin-1 blocks the prosurvival autophagy pathway in cancer cells. Peptide Sequence: N/A Appearance: White solid Formulation: N/A CAS Number: 1262888-28-7 Molecular Formula: C₁₅H₁₁F₂N₃ Molecular Weight: 271.26 Purity: ≥97% by HPLC Solubility:DMSO (~ 100 mM) Storage Temp.: -20°C Shipping Conditions: gel pack Handling: Protect from air and light SMILES: N/A InChi: N/A InChi Key: N/A PubChem CID: N/A MDL Number: N/A USAGE: For Research Use Only! Not For Use in Humans.
