HKSC Heat-killed S. cerevisiae HKSC is a heat-killed preparation of Saccharomyces cerevisiae. HKSC activates the β-glucan specific dectin-1 receptor, which is expressed on phagocytes. β-Glucans are glucose polymers found in the cell walls of fungi. Dectin-1 binds and internalizes β-glucans and mediates the activation of NF-κB and subsequent secretion of proinflammatory cytokines. Specificity: Dectin-1 agonist Working concentration: 108 cells/ml Endotoxin level: EndoFit™ (<0.001 EU/μg)