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HKSA
Heat Killed Staphyloccocus aureus
HKSA is a lyophilized heat-killed preparation of Staphyloccocus aureus, a Gram-positive extra-cellular growing bacterium. HKSA is recognized mainly by TLR2. HKSA induces tolerance to a secondary HKSA stimulation but causes priming to LPS, suggesting a differential regulation of cytokines and chemokines in gram-positive- and gram-negative-induced inflammatory events.
Specificity: TLR2 agonist
Working concentration: 106-108 cells/ml
Solubility: Insoluble (resuspended HKSA results in a cloudy suspension) |