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HKLM
Heat Killed Listeria monocytogenes
HKLM is a freeze-dried heat-killed preparation of Listeria monocytogenes (LM), a facultative intracellular Gram-positive bacterium. Infection with LM induces the secretion of inflammatory cytokines, such as TNF, IL-12, and several chemokines, allowing the recruitment and activation of immune cells. This response is mediated mainly by the interaction between MyD88 and TLR2.
HKLM is also available on ready-to-use 8-well strips pre-coated at 7 different concentrations and a negative control.
Specificity: TLR2 agonist
Working concentration: 107-108 cells/ml
Solubility: Insoluble (resuspended HKLM results in a cloudy suspension) |