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HKHP
Heat Killed Helicobacter pylori
Helicobacter pylori, a Gram negative bacterium, is an important human pathogen that causes gastritis and is strongly associated with peptic ulcer, gastric adenocarcinoma, and mucosa-associated lymphoid tissue lymphoma. Heat-killed Helicobacter pylori (HKHP) induces the production of IL-8 through the activation of the ERK and p38 MAPK pathway. TLR2 was shown to be the sensor involved in HKHP-mediated secretion of IL-8 in monocytes [1].
Specificity: TLR2 agonist
Working concentration: 106-108 cells/ml
Solubility: Insoluble (resuspended HKHP results in a cloudy suspension) |