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PP1 Analog
4-Amino-1-tert-butyl-3-(1′-naphthyl)pyrazolo[3,4-d]pyrimidine, 1-Na PP1, 1-NA-PP1
A potent, reversible, ATP-competitive, and cell-permeable inhibitor of Src-family tyrosine kinases that is > 800 times more selective for the I338G mutant v-Src (IC50 = 1.5 nM) compared to wild-type v-Src (IC50 = 1.0 µM). Also inhibits wild-type Fyn (IC50 = 600 nM). Also available in InSolution™ format (Cat. No. 529605).
产品信息
Form Off-white solid
Primary Target I338G mutant v-Src
Primary Target IC50 1.5 nM
Secondary target wild-type v-Src (IC50 = 1 µM), wild-type Fyn (IC50 = 600 nM)
Molar mass 317.4
Packaged under inert gas 是的
Cell permeable 是的
Purity ≥99% by HPLC
Solubility DMSO
Chemical formula C19H19N5
CAS number 221243-82-9
Declaration
Not available for sale in the United States.
商店和运输信息
Storage -20°C
Ship Ambient Temperature Only
Standard Handling |