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Anti-RBMS1(MSSP-1), clone 4D11
Species Reactivity Key Applications Host Format Antibody Type
H, M WB, ICC Mouse Purified Monoclonal Antibody
Description:
Anti-RBMS1(MSSP-1) Antibody, clone 4D11
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Specificity:
This antibody detects RBMS1 (MSSP-1).
Molecular Weight:
~50 kDa
Immunogen:
GST-tagged recombinant protein corresonding to RBMS1 (MSSP-1).
Clone:
4D11
Isotype:
IgG2bκ
Background Information:
RNA-binding motif, single-stranded-interacting protein 1 (RBMS1 or MSSP-1) is a single-stranded DNA binding protein that is characterized by the presence of two sets of ribonucleoprotein consensus sequence (RNP-CS) that contain conserved motifs, RNP1 and RNP2, originally described in RNA binding proteins, and required for DNA binding. At the developmental stage, RBMS1 (MSSP-1) is expressed at its highest levels during the G1 to S transition of the cell cycle and is most commonly found in placenta, lung and heart tissue. RBMS1 (MSSP-1) has been implicated in such diverse functions as DNA replication, gene transcription, cell cycle progression and apoptosis.
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Species Reactivity:
Human
Mouse
Species Reactivity Note:
Demonstrated to react with human and mouse.
Application Notes:
Immunocytochemistry Analysis: A previous lot of this antibody was used in confocal fluorescent analysis of NIH/3T3 and A431 cells (See page 2).
Control:
MCF-7 cell lysate
Quality Assurance:
Evaluated by Western Blot in MCF-7 cell lysate.
Western Blot Analysis: 1-2 µg/mL of this antibody detected RBMS1 (MSSP-1) on 15 µg of MCF-7 cell lysate.
Purification Method:
Protein G purfied
Presentation:
Purified mouse monoclonal IgG2bκ in buffer containing 0.1 M Tris-Glycine (pH7.4), 150 mM NaCl with 0.05% sodium azide.
Storage Conditions:
Stable at 2-8°C for 1 year from date of receipt.
UniProt Number:
P29558
Entrez Gene Number:
NP_002888.1
Gene Symbol:
MGC15146
MGC3331
MSSP
MSSP-1
MSSP-2
MSSP-3
MSSP1
SCR2
YC1
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Alternate Names:
RNA binding motif, single stranded interacting protein 1
Single-stranded DNA-binding protein MSSP-1
Suppressor of CDC2 with RNA-binding motif 2
c-myc gene single strand binding protein 2
suppressor of cdc 2 (cdc13) with RNA binding motif 2
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Usage Statement:
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Key Applications:
Western Blotting
Immunocytochemistry
Entrez Gene Summary:
This gene encodes a member of a small family of proteins which bind single stranded DNA/RNA. These proteins are characterized by the presence of two sets of ribonucleoprotein consensus sequence (RNP-CS) that contain conserved motifs, RNP1 and RNP2, originally described in RNA binding proteins, and required for DNA binding. These proteins have been implicated in such diverse functions as DNA replication, gene transcription, cell cycle progression and apoptosis. Several transcript variants, resulting from alternative splicing and encoding different isoforms, have been described. A pseudogene for this locus is found on chromosome 12.
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