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Anti-ADP-Ribosylation Factor 6, clone 6ARF01
Recommended Replacement for: MAB1131
Species Reactivity Key Applications Host Format Antibody Type
H WB Mouse Purified Monoclonal Antibody
Description:
Anti-ADP-Ribosylation Factor 6 Antibody, clone 6ARF01
Replaces:
MAB1131
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Specificity:
Recognizes ADP-ribosylation factor (ARF) 6.
Molecular Weight:
Approx. 19-20 kDa
Immunogen:
Recombinant human ARF6 protein.
Clone:
6ARF01
Isotype:
IgG
Background Information:
ADP-Ribosylation Factor 6 (ARF6) is a GTP-binding protein that functions as a regulator of cytoskeleton remodeling and endocytic recycling. ARF6 is an allosteric activator of cholera toxin catalytic subunit, an ADP-ribosyltransferase. It may also be involved in the modulation of vesicle budding and uncoating with the Golgi apparatus.
Species Reactivity:
Human
Species Reactivity Note:
Reacts with human.
Control:
NIH/3T3 Cell Lysate
Quality Assurance:
Evaluated in Western Blot on NIH/3T3 cell lysates.
Western Blot Analysis: 1:500 dilution of this antibody detected ARF6 in 10 µg of NIH/3T3 cell lysate.
Purification Method:
Protein G chromatography
Presentation:
Purified monoclonal IgG ascites in 10 mM PBS, pH 7.4, with 0.2% BSA and 0.09% sodium azide.
Storage Conditions:
Maintain refrigerated at 2-8ºC in undiluted aliquots for up to 12 months from date of receipt.
UniProt Number:
P62330
Entrez Gene Number:
P62330
Gene Symbol:
DKFZp564M0264
Alternate Names:
ADP-ribosylation factor 6
Usage Statement:
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Key Applications:
Western Blotting
UniProt Summary:
FUNCTION: SwissProt: P62330 # GTP-binding protein that functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP- ribosyltransferase. Involved in protein trafficking; may modulate vesicle budding and uncoating within the Golgi apparatus.
SIZE: 175 amino acids; 20082 Da
SUBUNIT: Interacts with ARHGAP21, DDEF2, PIP5K1C and UACA.
SIMILARITY: SwissProt: P62330 ## Belongs to the small GTPase superfamily. Arf family.
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Product Name:
Anti-ADP-Ribosylation Factor 6, clone 6ARF01
Concentration:
Please refer to the Certificate of Analysis for the lot-specific concentration.
Antibody Type:
Monoclonal Antibody
Qty/Pk:
100 μg
Format:
Purified
Host:
Mouse
Applications:
Anti-ADP-Ribosylation Factor 6 Antibody, clone 6ARF01 is a Mouse Monoclonal Antibody for detection of ADP-Ribosylation Factor 6 also known as ADP-ribosylation factor 6 & has been validated in WB. |