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Anti-Ubiquitinylated proteins Antibody, clone FK2
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REFERENCES
The deubiquitinating enzyme USP36 controls selective autophagy activation by ubiquitinated proteins.
Taillebourg, Emmanuel, et al. (2012) Autophagy, 8: (2012)
Mutations at a single codon in Mad homology 2 domain of SMAD4 cause Myhre syndrome.
Carine Le Goff,Clémentine Mahaut,Avinash Abhyankar,Wilfried Le Goff,Valérie Serre,Alexandra Afenjar,Anne Destrée,Maja di Rocco,Delphine Héron,Sébastien Jacquemont,Sandrine Marlin,Marleen Simon,John Tolmie,Alain Verloes,Jean-Laurent Casanova,Arnold Munnich,Valérie Cormier-Daire (2012) Nature genetics.44
RNF8 transduces the DNA-damage signal via histone ubiquitylation and checkpoint protein assembly.
Huen, Michael S Y, et al. (2007) Cell, 131: 901-14 (2007)
Production and characterization of monoclonal antibodies specific to multi-ubiquitin chains of polyubiquitinated proteins.
Fujimuro, M, et al. (1994) FEBS Lett., 349: 173-80 (1994)
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Species Reactivity Key Applications Host Format Antibody Type
A ELISA, IF, IP, WB Mouse Purified Monoclonal Antibody
Description:
Anti-Ubiquitinylated proteins Antibody, clone FK2
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Trade Name:
Upstate (Millipore)
Specificity:
Recognizes mono- and poly ubiquitinylated proteins, but not free ubiquitin.
Immunogen:
Poly-ubiquitinylated-lysozyme.
Isotype:
IgG1
Species Reactivity:
All
Presentation:
100 µL of purified immunoglobulin in PBS containing 0.1% sodium azide. Dilute to working strength with phosphate buffered saline pH 7.2-7.4.
Storage Conditions:
Stable for 1 year at -20°C from date of shipment for up to 12 months.
Usage Statement:
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Key Applications:
ELISA
Immunofluorescence
Immunoprecipitation
Western Blotting
Brand Family:
Upstate
Product Name:
Anti-Ubiquitinylated proteins Antibody, clone FK2
Concentration:
Please refer to the Certificate of Analysis for the lot-specific concentration.
Antibody Type:
Monoclonal Antibody
Qty/Pk:
100 µL
Format:
Purified
Host:
Mouse
Applications:
This Anti-Ubiquitinylated proteins Antibody, clone FK2 is validated for use in ELISA, IF, IP, WB for the detection of Ubiquitinylated proteins |