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产品编号 G3632
CAS号 1405-41-0
庆大霉素 硫酸盐
Gentamicin sulfate salt
potency: ≥590 μg Gentamicin base per mg
Application
Used as a selection agent (gentamicin-resistance gene) in molecular biology applications.
Biochem/physiol Actions
Mode of action: Gentamicin causes codon misreading by binding to the 30S ribosomal subunit, blocking the translocation of peptidyl-tRNA from the acceptor site to the donor site.1,2 The bactericidal effect of gentamicin on Pseudomonas aeruginosa is exerted by the binding of gentamicin to the outer membrane, where it displaces natural cations, destabilizes the membrane, and forms holes in the cell surface.3
Antimicrobial spectrum: Gram-negative bacteria, Staphylococcus aureus and other Gram-positive bacteria
potency ≥590 μg Gentamicin base per mg
shelf life 2 yr at 2-8 °C ( for sterile filtered solutions.)
concentration 50 μg/mL in H2O ( is the recommended working concentration for eukaryotic cell culture)
storage temp. 2-8°C
Appearance (Color) White to Off-White
Appearance (Form) Powder
Solubility (Color) Colorless to Faint Yellow
Solubility (Turbidity) Clear to Very Slightly Hazy
50 mg/ml in H2O
Infrared spectrum Conforms to Structure
Water (by Karl Fischer) < 15 % _
µg Gentamicin base/mg > 590 _
Dried basis
Recommended Retest Period -------------------------
6 Years |