InSolution Fluvastatin, Sodium Salt

InSolution™ Fluvastatin, Sodium Salt
A synthetic, competitive inhibitor of HMG-CoA reductase that acts as anti-hypercholesterolemic agent. Unlike Lovastatin (Cat. No. 438185), Mevastatin (Cat. No. 474700), and Simvastatin (Cat. No. 567020), it does not require activation prior to use for in vitro studies. Reduces the basal MMP-1 levels in culture media of endothelial cells in a time- and dose-dependent manner. Fluvastatin is metabolized in the liver, primarily via hydroxylation of the indole ring at the 5- and 6-positions. N-Dealkylation and β-oxidation of the side-chain also occurs. The hydroxy metabolites are also reported to have some pharmacologic activity.
产品信息
Form  Liquid
Formulation  A 10 mM (10 mg/2.13 ml) solution of Fluvastatin, Sodium Salt (344095) in H2O.
Primary Target  HMG-CoA reductase
Molar mass  433.5
Protect from Light  是的
Avoid freeze/thaw  是的
Packaged under inert gas  是的
Reversible  是的
Purity  ≥98% by HPLC
CAS number  93957-55-2
商店和运输信息
Storage  ≤ -70°C
Ship  Dry Ice Only
Standard Handling