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4-Cyano-3-methylisoquinoline
A potent, cell-permeable, reversible, and specific inhibitor of protein kinase A (IC50 = 30 nM). Inhibition is competitive with respect to ATP. Shows only weak inhibitory activities against Ca2+-dependent protein kinase (CDPK), MLCK, PKC, and cyclic nucleotide-binding phosphatase.
产品信息
Form White solid
Primary Target PKA
Primary Target IC50 30 nM
Molar mass 168.2
Packaged under inert gas 是的
Cell permeable 是的
Purity ≥95% by HPLC
Solubility DMSO
Chemical formula C11H8N2
CAS number 161468-32-2
商店和运输信息
Storage +2°C to +8°C
Ship Ambient Temperature Only
Standard Handling |