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AMPK Activator, D942
A potent AMPK activator
Product Overview
Product Name: AMPK Activator, D942
Alternate Name/Synonyms: 5-(3-(4-(2-(4-Fluorophenyl)ethoxy)phenyl)propyl)furan-2-carboxylic acid
Description: Cell-permeable. A potent activator of AMPK (AMP-activated protein kinase). The activation of AMPK was achieved through inhibition of NAD(P)H dehydrogenase [quinone] 1 (complex I). D942 increases glucose uptake in L6 myocytes, and inhibits CCL2-induced mTORC1 activity and survivin expression in human prostate cancer PC-3 cells.
Peptide Sequence: N/A
Appearance: Light yellow solid
Formulation: N/A
CAS Number: 849727-81-7
Molecular Formula: C₂₂H₂₁FO₄
Molecular Weight: 368.4
Purity: ≥98% by HPLC
Solubility:DMSO (10 mg/ml)
Storage Temp.: -20 ̊C
Shipping Conditions: gel pack
Handling: Protect from air and light
SMILES: C1=CC(=CC=C1CCCC2=CC=C(O2)C(=O)O)OCCC3=CC=C(C=C3)F
InChi: InChI=1S/C22H21FO4/c23-18-8-4-17(5-9-18)14-15-26-19-10-6-16(7-11-19)2-1-3-20-12-13-21(27-20)22(24)25/h4-13H,1-3,14-15H2,(H,24,25)
InChi Key: MPLLLQUZNJSVTK-UHFFFAOYSA-N
PubChem CID: 16760291
MDL Number: N/A
USAGE: For Research Use Only! Not For Use in Humans. |