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Biotin-HPDP
A sulfhydryl reactive biotinylation reagent
Product Overview
Product Name: Biotin-HPDP
Alternate Name/Synonyms: N-[6-(Biotinamido)hexyl]-3’-(2’-pyridyldithio)-propionamide; Biotin-HPDP, pyridyldithiol-biotin, pyridyldisulfide-biotin
Description: KEY FEATURES:
• HPDP contains a dithiopyridyl group which is reactive towards sulfhydryl groups (-SH) such as in cysteine (C) side chain to form stable disulfide bond
• Contains a spacer arm with a length of 29.2 Å that prevents steric hindrance to biotin labeling
• The spacer is cleavable at the disulfide bond with reducing agent, such as DTT, TCEP, etc.
• Must be dissolved in an organic solvent such as DMF or DMSO before dilution with aqueous buffers
APPLICATIONS:
• Ideal for biotinylating antibody or protein for use in protein detection, purification or immobilization.
Peptide Sequence: N/A
Appearance: White to Off-white Solid
Formulation: N/A
CAS Number: 129179-83-5
Molecular Formula: C₂₄H₃₇N₅O₃S₃
Molecular Weight: 539.78
Purity: ≥90% by NMR
Solubility:DMSO or DMF
Storage Temp.: +4 ̊C
Shipping Conditions: Gel Pack
Handling: Protect from moisture
SMILES: C1C2C(C(S1)CCCCC(=O)NCCCCCCNC(=O)CCSSC3=CC=CC=N3)NC(=O)N2
InChi: InChI=1S/C24H37N5O3S3/c30-20(10-4-3-9-19-23-18(17-33-19)28-24(32)29-23)25-13-6-1-2-7-14-26-21(31)12-16-34-35-22-11-5-8-15-27-22/h5,8,11,15,18-19,23H,1-4,6-7,9-10,12-14,16-17H2,(H,25,30)(H,26,31)(H2,28,29,32)/t18?,19-,23?/m0/s1
InChi Key: QLPHBNRMJLFRGO-KPRXVCGWSA-N
PubChem CID: 46783562
MDL Number: MFCD00867240
USAGE: For Research Use Only! Not For Use in Humans. |