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KT5720
A potent and selective Protein kinase A (PKA) inhibitor
Product Overview
Product Name: KT5720
Alternate Name/Synonyms: (9R,10S,12S)-2,3,9,10,11,12-Hexahydro-10-hydroxy-9-methyl-1-oxo-9,12-epoxy-1H-diindolo[1,2,3-fg:3',2',1'-kl]pyrrolo[3,4-i][1,6]benzodiazocine-10-carboxylic acid, hexyl ester
Description: A derivative of the protein kinase inhibitor K252a (Cat. No. 2013). Acts as a potent, selective, ATP-competitive inhibitor of protein kinase A (PKA) (Ki = 60 nM). Has no effect on PKC, PKG and MLCK.
Peptide Sequence: N/A
Appearance: Colorless solid
Formulation: N/A
CAS Number: 108068-98-0
Molecular Formula: C₃₂H₃₁N₃O₅
Molecular Weight: 537.61
Purity: ≥98% by HPLC
Solubility:DMSO (~50 mM)
Storage Temp.: -20 ̊C
Shipping Conditions: gel pack
Handling: Protect from air and moisture
SMILES: CCCCCCOC(=O)C1(CC2N3C4=CC=CC=C4C5=C6C(=C7C8=CC=CC=C8N(C7=C53)C1(O2)C)CNC6=O)O
InChi: InChI=1S/C32H31N3O5/c1-3-4-5-10-15-39-30(37)32(38)16-23-34-21-13-8-6-11-18(21)25-26-20(17-33-29(26)36)24-19-12-7-9-14-22(19)35(28(24)27(25)34)31(32,2)40-23/h6-9,11-14,23,38H,3-5,10,15-17H2,1-2H3,(H,33,36)
InChi Key: ZHEHVZXPFVXKEY-UHFFFAOYSA-N
PubChem CID: 3844
MDL Number: MFCD00132118
USAGE: For Research Use Only! Not For Use in Humans. |