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PCSK9 Antibody
Polyclonal Antibody to detect PCSK9 in human, mouse and rat samples
Product Overview
Product Name: PCSK9 Antibody
Antibody Target: PSCK9
Alternative Name: PCSK9, FH3, HCHOLA3, LDLCQ1, NARC1, PC9
Host: Rabbit
Antibody Type: Polyclonal
Isotype: Rabbit IgG
Immunogen: Recombinant Human Cell Expressed Human PCSK9 Protein
Accession#: Q8NBP7
Gene ID: 255738
Appearance: Lyophilized powder
Concentration: N/A
Formulation: Lyophilized from 0.22 μm filtered solution in 50 mM tris, 100 mM glycine, pH 7.0 with trehalose and 0.05% sodium azide as protectant before lyophilization.
Purification: Protein A/G purified
Species Reactivity: Human
Application: Western blot, ELISA
Positive Control: N/A
Application & Usage: Western blot: 0.5 - 2.0 µg/ml, ELISA: 0.2 – 1 µg/ml
Storage Temp.: -20 °C
Shipping: gel pack
Background Descriptions: Proprotein convertase subtilisin/kexin type 9 (PCSK9), is an enzyme which in humans is encoded by the PCSK9 gene. This gene encodes a proprotein convertase belonging to the proteinase K subfamily of the secretory subtilase family. This protein plays a major regulatory role in cholesterol homeostasis. PCSK9 binds to the epidermal growth factor-like repeat A (EGF-A) domain of the low-density lipoprotein receptor (LDLR), inducing LDLR degradation. PCSK9 may also have a role in the differentiation of cortical neurons. Mutations in this gene have been associated with a rare form of autosomal dominant familial hypercholesterolemia (HCHOLA3).
Handling: The antibody solution should be gently mixed before use
USAGE: For Research Use Only! Not For Use in Humans. |