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GSAP Antibody
Polyclonal antibody to detect GSAP in human mouse and rat samples
Product Overview
Product Name: GSAP Antibody
Antibody Target: GSAP
Alternative Name: PION, Gamma-secretase-activating protein, Protein pigeon homolog
Host: Rabbit
Antibody Type: Polyclonal
Isotype: Rabbit IgG
Immunogen: Synthetic peptide close to C-terminal of GSAP
Accession#: A4D1B5
Gene ID: 54103
Appearance: Colorless liquid
Concentration: 0.5 mg/ml
Formulation: 100 µg (0.5 mg/ml) polyclonal antibody in PBS pH 7.2, containing 30% glycerol, 0.5% BSA, 5mM EDTA and 0.01% thimerosal.
Purification: Affinity Purified Antibody
Species Reactivity: Human, mouse, rat
Application: Western blot
Positive Control: Western blot: Mouse 3T3 cell lysate
Application & Usage: Western Blot analysis (1-4 µg/ml).
Storage Temp.: -20 °C
Shipping: gel pack
Background Descriptions: GSAP, gamma-secretase activating protein interacts with gamma secretase which chops up the amyloid precursor protein to senile plaques in Alzheimer’s disease. GSAP was found to increase the production amyloid peptide. Immunohistochemistry to identify GSAP in brain can demonstrate its abundance in certain regions of damage, and is usually morphologically changed throughout the progression of Alzheimer's disease. GSAP can be used as a qualitative biomarker of Alzheimer's disease progression, and is regularly considered one of the best targets of therapies to diminish the effects of Alzheimer's disease in affected individuals.
Handling: The antibody solution should be gently mixed before use
USAGE: For Research Use Only! Not For Use in Humans. |