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Artemis (DCLREIC) Antibody
Polyclonal antibody to detect Artemis in human, mouse and rat samples
Product Overview
Product Name: Artemis (DCLREIC) Antibody
Antibody Target: Artemis
Alternative Name: DNA cross-link repair 1C protein, SNM1-like protein
Host: Rabbit
Antibody Type: Polyclonal
Isotype: Rabbit IgG
Immunogen: Synthetic peptide surrounding the C-terminal (BV-M21)
Accession#: Q96SD1
Gene ID: 64421
Appearance: Colorless liquid
Concentration: 0.5 mg/ml
Formulation: 100 µg (0.5 mg/ml) of antibody in PBS, 0.01 % BSA, 0.01 % thimerosal, and 50 % glycerol, pH 7.2
Purification: Affinity purified
Species Reactivity: Human, mouse, rat
Application: Western blot
Positive Control: 3T3 cell lysate
Application & Usage: Western blot: 1:200
Storage Temp.: -20 °C
Shipping: gel pack
Background Descriptions: Artemis is a 78 kDa protein, belonging to metallo-beta-lactamase superfamily. It is involved in endonuclease activity to break DNA hairpins. It also has been reported that the C-terminus of Artemis interacts with DNA binding domain of Ligase IV directly. Ligase IV is a key enzyme in DNA repair and V(D)J recombination. Thus, Artemis is a novel protein that is involved in V(D)J recombination/DNA repair. Mutations cause human T-B-severe combined immunodeficiency associated with increased cellular radiosensitivity (RS-SCID).
Handling: The antibody solution should be gently mixed before use
USAGE: For Research Use Only! Not For Use in Humans. |