Human Recombinant Thioredoxin A protein involved in redox signaling Product Overview Product Name: Human Recombinant Thioredoxin Alternate Name/Synonyms: TXN, TRX, TRX1 Gene Symbol: TNXL1 Accession #: O43396 Gene ID: 9352 Source: E. coli Appearance: Liquid Physical Form Description: 1 mg/ml solution in PBS (pH 7.4). Molecular Weight: 11.7 kDa (105 aa) Purity by SDS-PAGE: ≥95% Purity by HPLC: N/A Endotoxin Level: < 1.0 EU per 1 μg of protein (determined by LAL method) Biological Activity: > 7-10 A650/min/mg Reconstitution Instructions: N/A Storage Temp.: -80°C Shipping: Gel Pack Background Information: Thioredoxin (Trx) is a low molecular weight redox protein. Trx contains a redox active disulfide/dithiol group within the conserved Cys-Gly-Pro-Cys active site. It is involved in the first unique step in DNA synthesis. Trx also provides control over a number of transcription factors affecting cell proliferation and death through a mechanism referred to as redox regulation. Recombinant human thioredoxin-1 was overexpressed in E. coli and purified by using conventional chromatography techniques. Amino Acid Sequence: MVKQIESKTA FQEALDAAGD KLVVVDFSAT WCGPCKMIKP FFHSLSEKYS NVIFLEVDVD DCQDVASECE VKCMPTFQFF KKGQKVGEFS GANKEKLEAT INELV Handling: Centrifuge the vial prior to opening USAGE: For Research Use Only! Not For Use in Humans.
