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Anti-Rac3
Description:
Anti-Rac3 Antibody
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Molecular Weight:
~20 kDa observed. An uncharacterized band may appear at ~100 kDa and ~115 kDa in some lysates.
Immunogen:
KLH-conjugated linear peptide corresponding to human Rac3.
Background Information:
RAC3 (Ras-related C3 botulinum toxin substrate 3; p21-Rac3) is a small GTPase belonging to the Rho family. It is found in the brain, heart, placenta and pancreas, and is localized to the plasma membrane where it cycles between an active GTP- and an inactive GDP-bound state. It is regulated by the Bcr protein. Rac3 activates effector molecules, such as p21-activated kinase, which are linked to the c-Jun amino-terminal kinase signaling pathway, and may promote tumor growth by this mechanism.
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Species Reactivity:
Human
Species Reactivity Note:
Demonstrated to react with Human. Predicted to react with Mouse and Rat based on 100% sequence homology.
Control:
MCF7 cell lysate.
Quality Assurance:
Evaluated by Western Blot in MCF7 cell lysate.
Western Blot Analysis: A 1:1,000 dilution of this antibody detected Rac3 in 10 µg of MCF7 cell lysate.
Purification Method:
Affinity purified
Presentation:
Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Storage Conditions:
Stable for 1 year at 2-8°C from date of receipt.
UniProt Number:
P60763
Entrez Gene Number:
NP_005043
Gene Symbol:
RAC3
Alternate Names:
Ras-related C3 botulinum toxin substrate 3
p21-Rac3
Usage Statement:
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Key Applications:
Western Blotting
Product Name:
Anti-Rac3
Concentration:
Please refer to the Certificate of Analysis for the lot-specific concentration.
Antibody Type:
Polyclonal Antibody
Qty/Pk:
100 μg
Format:
Affinity Purified
Host:
Rabbit |