Glutaminase Inhibitor, Compound 968 A cell-permeable benzophenanthridinone compound that acts as an allosteric and reversible inhibitor of mitochondrial glutaminase activity and represses the growth and invasive activity in glutaminase upregulated fibroblasts and in tumor cells (IC50 ≤ 10 µM in NIH3T3 cells stably expressing Dbl, Cdc42-F28L, Rac-F28L or RhoC-F30L mutants and in SKBR3 and MDA-MB231 cancer cells). Shown to effectively shrink tumor size in P-493 B xenografted mouse model (200 µg per inj. i.p., 12 days). Also available as a 10 mM solution in DMSO (Cat. No. 506073). 产品信息Form White powderMolar mass 475.4Protect from Light 是的Packaged under inert gas 是的Purity ≥99% by HPLCSolubility DMSOChemical formula C27H27BrN2O商店和运输信息Storage -20°CShip Shipped at Ambient Temperature or with Blue Ice or with Dry Ice Standard Handling
