Glyphosine A glycine-phosphonic acid compound, negatively charged at neutral pH, with immunomodulatory and anti-diabetic properties. Shown to enhance CD4+ T cell response to B-chain of insulin (amino acids 9-23) even at 10 nM levels (EC50 = 70.6 nM). Occupies a pocket 9 of I-Ag7 (the class II molecules of the diabetes-prone NOD mice) and alters TCR/peptide-MHC affinity. Stimulates IL-10 secretion in splenocyes in non-obese diabetic (NOD) mice. Daily administration of glyphosine is shown to delay the onset of diabetes in NOD mice. Acts as a competitive inhibitor of phoshoenolpyruvate carboxylase in plants. 产品信息 Form White solid Molar mass 263.1 Protect from Light 是的 Hygrocopic 是的 Packaged under inert gas 是的 Purity ≥98% by NMR Solubility H2O Chemical formula C4H11NO8P2 CAS number 2439-99-8 商店和运输信息 Hazardous Materials Attention: Due to the nature of the Hazardous Materials in this shipment, additional shipping chargesmay be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges. Storage +2°C to +8°C Ship Ambient Temperature Only Corrosive
