Anaphase-Promoting Complex Inhibitor, TAME TAME is a potent ubiquitin ligase inhibitor that specifically blocks Anaphase-Promoting Complex (APC) activation by directly binding to APC and disrupts the IR-tail-dependent interactions between APC and its activator proteins Cdc20 or Cdh1. It stabilizes APC substrates and is shown to inhibit cyclin proteolysis in mitotic Xenopus egg extract with an IC50 = 12 µM. 产品信息 Form White solid Molar mass 378.87 Protect from Light 是的 Packaged under inert gas 是的 Purity ≥98% by HPLC Solubility DMSO or EtOH Chemical formula C14H22N4O4S · HCl CAS number 1784-03-8 商店和运输信息 Storage +2°C to +8°C Ship Ambient Temperature Only Standard Handling
