Sphingosine Kinase Inhibitor, SKI-I

Sphingosine Kinase Inhibitor, SKI-I
A non-lipid pan-sphingosine kinase (SK) inhibitor
Product Overview
Product Name: Sphingosine Kinase Inhibitor, SKI-I
Alternate Name/Synonyms: 5-naphthalen-2-yl-2H-pyrazole-3-carboxylic acid (2-hydroxy-naphthalen-1-ylmethylene)-hydrazide
Description: Cell-permeable. SKI-I is a non-lipid pan-sphingosine kinase (SK) inhibitor that inhibits both SK1 and SK2 to suppress the production of pro-mitogenic sphingosine 1-phosphate (S1P) and promote cell death. Also induces autophagy.
Peptide Sequence: N/A
Appearance: Pale yellow solid
Formulation: N/A
CAS Number: 306301-68-8
Molecular Formula: C₂₅H₁₈N₄O₂
Molecular Weight: 406.44
Purity: ≥90% by NMR
Solubility:DMSO
Storage Temp.: -20°C
Shipping Conditions: gel pack
Handling: Protect from air and light
SMILES: O=C(N/N=C/C1C2CCCCC2CCC1O)C3CC(NN3)C4CCC5CCCCC5C4
InChi: InChI=1S/C25H18N4O2/c30-24-12-11-17-6-3-4-8-20(17)21(24)15-26-29-25(31)23-14-22(27-28-23)19-10-9-16-5-1-2-7-18(16)13-19/h1-15,30H,(H,27,28)(H,29,31)/b26-15+
InChi Key: XOXCTLAKMCIWCF-CVKSISIWSA-N
PubChem CID: N/A
MDL Number: N/A
USAGE: For Research Use Only! Not For Use in Humans.