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(±)-Thalidomide
A selective inhibitor of tumor necrosis factor α (TNF-α) synthesis
Product Overview
Product Name: (±)-Thalidomide
Alternate Name/Synonyms: (RS)-2-(2,6-dioxopiperidin-3-yl)-1H-isoindole-1,3(2H)-dione
Description: Cell-permeable. A teratogen and sedative-hypnotic with inherent anti-inflammatory properties. A selective inhibitor of tumor necrosis factor α (TNF-α) synthesis. Thalidomide initiates its teratogenic effects by binding to cereblon (CRBN), a thalidomide-binding protein, and inhibiting the associated ubiquitin ligase activity.
Peptide Sequence: N/A
Appearance: White solid
Formulation: N/A
CAS Number: 50-35-1
Molecular Formula: C₁₀H₁₃N₂O₄
Molecular Weight: 258.23
Purity: ≥98% by TLC
Solubility:DMSO (5 mg/ml)
Storage Temp.: -20°C
Shipping Conditions: gel pack
Handling: Protect from air and light
SMILES: C1CC(=O)NC(=O)C1N2C(=O)C3=CC=CC=C3C2=O
InChi: InChI=1S/C13H10N2O4/c16-10-6-5-9(11(17)14-10)15-12(18)7-3-1-2-4-8(7)13(15)19/h1-4,9H,5-6H2,(H,14,16,17)
InChi Key: UEJJHQNACJXSKW-UHFFFAOYSA-N
PubChem CID: 5426
MDL Number: MFCD00153873
USAGE: For Research Use Only! Not For Use in Humans. |