|
Honokiol
A NF-kappaB modulator
Product Overview
Product Name: Honokiol
Alternate Name/Synonyms: 2-(4-hydroxy-3-prop-2-enyl-phenyl)- 4-prop-2-enyl-phenol; HNK; Houpa
Description: Present as an active principle in the plant Magnolia grandiflora. Displays anxiolytic, antithrombotic, anti-tumor properties, etc. modulates the NF-κB activation pathway, an upstream effector VEGF, COX-2, and MCL1, all significant pro-angiogenic and survival factors. Honokiol induces caspase-dependent apoptosis in a TRAIL-mediated manner, and potentiates the pro-apoptotic effects of doxorubicin and other etoposides.
Peptide Sequence: N/A
Appearance: White solid
Formulation: N/A
CAS Number: 35354-74-6
Molecular Formula: C₁₈H₁₈O₂
Molecular Weight: 266.33
Purity: ≥97% by HPLC
Solubility:DMSO (10 mg/ml) or EtOH
Storage Temp.: -20°C
Shipping Conditions: gel pack
Handling: Protect from air and moisture
SMILES: C=CCC1=CC(=C(C=C1)O)C2=CC(=C(C=C2)O)CC=C
InChi: InChI=1S/C18H18O2/c1-3-5-13-7-9-18(20)16(11-13)14-8-10-17(19)15(12-14)6-4-2/h3-4,7-12,19-20H,1-2,5-6H2
InChi Key: FVYXIJYOAGAUQK-UHFFFAOYSA-N
PubChem CID: 72303
MDL Number: MFCD00016674
USAGE: For Research Use Only! Not For Use in Humans. |