ssRNA-DR/LyoVec™ ssRNA-DR is a short single stranded RNA (<30 bp) that contains two copies of the 9 mer sequence GUCCUUCAA. This sequence is a putative immunostimulatory motif recognized by human TLR8 and mouse TLR7 that induces type I interferons [1]. ssRNA-DR is provided pre-complexed with the cationic lipid LyoVec™ to facilitate its uptake. Specificity: human TLR8/mouse TLR7 agonist Working Concentration: 1 - 10 μg/ml Sequence: ssRNA-DR 5’-UsGsUsCsCsUsUsCsAsAsUsGsUsCsCsUsUsCsAsA-3’ (“s” depicts a phosphothioate linkage) Endotoxin level: EndoFit™ (<0.001 EU/µg) Solubility: 0.05 mg/ml in water