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LPS-RS
LPS from R. sphaeroides
Lipopolysaccharide from the photosynthetic bacterium Rhodobacter sphaeroides (LPS-RS) is a potent antagonist of lipopolysaccharide (LPS) from pathogenic bacteria [1].
Complete competitive inhibition of LPS activity is possible at a 100-fold excess of the antagonist.
LPS-RS does not induce TLR4 signaling but is detected by the LAL assay, the standard endotoxin detection assay.
InvivoGen provides LPS-RS with two grades of purity: standard and ultrapure.
On the contrary to LPS-RS standard, ultrapure LPS-EK does not activate the TLR2 pathway.
1. Coats SR. et al., 2005. MD-2 mediates the ability of tetra-acylated and penta-acylated lipopolysaccharides to antagonize Escherichia coli lipopolysaccharide at the TLR4 signaling complex. J Immunol.;175(7):4490-8.
Specificity: TLR4 antagonist
LPS-RS standard is also a TLR2 agonist
Working concentration: 10 ng - 10 μg/ml
Endotoxin level: 1 x 106 EU/mg
Solubility: 5 mg/ml in water
InvivoGen provides LPS-RS with two grades of purity: Standard and Ultrapure |