Pam3CSK4 Synthetic triacylated lipoprotein Pam3CSK4 is a synthetic triacylated lipopeptide (LP) that mimics the acylated amino terminus of bacterial LPs. Pam3CSK4 is a potent activator of the proinflammatory transcription factor NF-κB. Activation is mediated by the interaction between TLR2 and TLR1 which recognize LPs with three fatty acids, a structural characteristic of bacterial LPs. Pam3CSK4 is also available on ready-to-use 8-well strips pre-coated at 7 different concentrations and a negative control. Specificity: TLR 1/2 agonist CAS number: 112208-00-1 Working concentration: 1 - 300 ng/ml Molecular formula: C81H156N10O13S Molecular weight: 1509.6 Endotoxin level: <0.001 EU/μg Solubility: 1 mg/ml in water