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分子生化试剂 >> 生化试剂 |
ODN M362
产品编号: |
tlrl-m362-1
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产品名称:
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ODN M362 .0 订购此产品 |
供应商:
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Invivogen |
规格: |
1 mg |
目录价: |
6902 |
库存状态: |
二周到货 |
CAS编号:
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应用范围: |
生化试验 |
种属来源: |
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相关信息: |
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ODN M362
Class C CpG oligonucleotide - Human / Murine TLR9 ligand
CpG ODNs are synthetic oligonucleotides that contain unmethylated CpG dinucleotides in particular sequence contexts (CpG motifs). These CpG motifs are present at a 20-fold greater frequency in bacterial DNA compared to mammalian DNA. CpG ODNs are recognized by Toll-like receptor 9 (TLR9) leading to strong immunostimulatory effects.
ODN M362 is a C-class CpG ODN specific for human / mouse TLR9.
Specificity: human / murine TLR9 agonist
Working concentration: 5 µM (10 μg/ml)
Solubility: 5 mg/ml in water
ODN M362 sequence
5’-tcgtcgtcgttc:gaacgacgttgat-3’ (25 mer)
Note: Bases are phosphorothioate (nuclease resistant), palindrome is underlined.
Quality control
- TLR9 activity is tested using HEK-Blue™ TLR9 cells.
- The absence of bacterial contamination (endotoxins, peptidoglycans) is controlled using HEK-Blue™ TLR2 and HEK-Blue™ TLR4 cells.
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