ssPolyU/LyoVec™ ssPolyU is a lyophilized preparation of single-stranded poly-uridine (polyU) complexed with the cationic lipid LyoVec™, to protect it from degradation and facilitate its uptake. PolyU is a synthetic ssRNA which when complexed to cationic lipids can substitute for viral RNAs in inducing IFN-α production in plasmacytoid dendritic cells (pDC). Specificity: human TLR8/mouse TLR7 agonist Working Concentration: 1- 10 μg/ml Endotoxin level: EndoFit™ (<0.001 EU/µg) Solubility: 0.05 mg/ml in water
