|
HKPA
Heat Killed P. aeruginosa
Pseudomonas aeruginosa is a virulent gram-negative pathogen that infects patients through the respiratory tract, in particular patients with cystic fibrosis. Heat-killed Pseudomonas aeruginosa (HKPA) initiates host inflammatory responses through TLR2 and TLR5 but not TLR4 [1,2]. The TLR5-mediated response was shown to be induced by flagellin while LPS appears to play an important role in the TLR2-mediated response.
Specificity: TLR2 agonist
Working concentration: 105-107 cells/ml
Solubility: Insoluble (resuspended HKPA results in a cloudy suspension) |