iE-DAP γ-D-Glu-mDAP (iE-DAP) is a dipeptide present in the peptidoglycan (PGN) of all Gram-negative and certain Gram-positive bacteria. iE-DAP is the minimal motif recognized by the intracellular receptor NOD1. Recognition of iE-DAP by NOD1 induces NF-κB activation and the production of inflammatory cytokines. iE-DAP provided by InvivoGen is chemically synthesized and tested using HEK-Blue™ NOD1. Note: iE-DAP is a mixture of γ-D-Glu-D-mDAP and γ-D-Glu-L-mDAP. Specificity: NOD1 agonist Working Concentration: 1 - 100 µg/ml Endotoxin level: <0.125 EU/ml Solubility: 10 mg/ml in water Formula: C12H21N3O7 Molecular weight: 319.31 Synonym: γ-D-glutamyl-meso-diaminopimelic acid