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Anti-MICAL-1, clone M1

产品编号: MABN93     查看说明书
产品名称: Anti-MICAL-1, clone M1  .0   订购此产品 
供应商: Millipore
规格: ***
目录价: 3,828.00
库存状态: 三周到货
CAS编号:
应用范围: 生化实验
种属来源:
相关信息:

Anti-MICAL-1, clone M1
Species Reactivity Key Applications Host Format Antibody Type
R, M  WB Mouse Purified Monoclonal Antibody
Description:
Anti-MICAL-1 Antibody, clone M1
Promotional Text:
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Molecular Weight:
~120 kDa observed. This protein has 3 isoforms with molecular weights of ~94, 56, and 15 kDa.
Immunogen:
GST-tagged recombinant protein corresponding to mouse MICAL-1.
Clone:
M1
Isotype:
IgG2aκ
Background Information:
MICAL-1 (Molecule Interacting with CasL 1) is a cytoskeletal regulator that links CasL to intermediate filaments. It interacts with rab1 and is associated with the Golgi apparatus and the intermediate filament cytoskeleton. MICAL-1 seems to play a part in semaphorin signaling to their plexin receptors which control morphological changes through F-actin reorganization.
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Species Reactivity:
Rat
Mouse
Species Reactivity Note:
Demonstrated to react with Rat and Mouse.
Application Notes:
Western Blot Analysis: 0.5 µg/mL from a representative lot detected MICAL-1 on 10 µg of rat skeletal muscle tissue lysate.
Control:
C2C12 cell lysate
Quality Assurance:
Evaluated by Western Blot in C2C12 cell lysate.
Western Blot Analysis: 0.5 µg/mL of this antibody detected MICAL-1 on 10 µg of C2C12 cell lysate.
Purification Method:
Protein G
Presentation:
Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Storage Conditions:
Stable for 1 year at 2-8°C from date of receipt.
UniProt Number:
Q8BGT6
Entrez Gene Number:
NP_803412
Gene Symbol:
Micall1
D15Mit260
Mirab13
Alternate Names:
MICAL-like protein 1
Molecule interacting with Rab13
MIRab13
Usage Statement:
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Key Applications:
Western Blotting
UniProt Summary:
FUNCTION: May be a cytoskeletal regulator.
SUBUNIT STRUCTURE: Binds to Rab13 (By similarity).
SUBCELLULAR LOCATION: Cytoplasm › cytoskeleton (By similarity).
SEQUENCE SIMILARITIES: Contains 1 CH (calponin-homology) domain.
Contains 1 LIM zinc-binding domain.
SEQUENCE CAUTION: The sequence BAC98229.1 differs from that shown. Reason: Erroneous initiation.
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Product Name:
Anti-MICAL-1, clone M1
Concentration:
Please refer to the Certificate of Analysis for the lot-specific concentration.
Antibody Type:
Monoclonal Antibody
Qty/Pk:
100 μg
Format:
Purified
Host:
Mouse
Applications:
This Anti-MICAL-1 Antibody, clone M1 is validated for use in WB for the detection of MICAL-1.

保存条件: 2-8℃
说明书地址: 点击查看详细
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上一个:Anti-Potassium Channel Kv1.2, clone K14/16[MABN77/***]
下一个:Anti-MICAL-3, clone M3[MABN94/***]
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