产品说明 A cell-permeable, reversible dipeptide aldehyde that reduces Aβ production by blocking γ-secretase activity in vitro (Aβ40 IC50 = 7.9 µM; Aβ42 IC50 = 7.6 µM) and in cultured CHO 2b-7 cells that stably overexpress APP695 (Aβ40 IC50 = 11.5 µM; Aβ42 IC50 = 8.3 µM). Also blocks the generation of CTFγ (γ-secretase-generated carboxyl-terminal fragment). Does not affect the formation of amyloid-β-precursor protein (APP). 产品信息 Peptide Sequence Z-Ile-Leu-CHO Form White solid Primary Target Aβ40 in vitro Primary Target IC50 7.9 µM Secondary target blocking γ-secretase activity in vitro (Aβ40 IC50 = 7.9 µM; Aβ42 IC50 = 7.6 µM) and in cultured CHO 2b-7 cells that stably overexpress APP695 (Aβ40 IC50 = 11.5 µM; Aβ42 IC50 = 8.3 µM) Protect from Light 是的 Packaged under inert gas 是的 Cell permeable 是的 Reversible 是的 Purity ≥95% by HPLC Chemical formula C20H30N2O4 Storage -20°C Ship Ambient Temperature Only Standard Handling