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G-SECRETASE INHIBITOR XII|γ-Secretase Inhibitor XII|原装

产品编号: 565773-5MG     查看说明书
产品名称: G-SECRETASE INHIBITOR XII|γ-Secretase Inhibitor XII|原装  .0   订购此产品 
供应商: Merck
规格: 5MG
目录价: 2211
库存状态: 3周到货
CAS编号:
应用范围: 生化实验
种属来源:
相关信息:

产品说明
A cell-permeable, reversible dipeptide aldehyde that reduces Aβ production by blocking γ-secretase activity in vitro (Aβ40 IC50 = 7.9 µM; Aβ42 IC50 = 7.6 µM) and in cultured CHO 2b-7 cells that stably overexpress APP695 (Aβ40 IC50 = 11.5 µM; Aβ42 IC50 = 8.3 µM). Also blocks the generation of CTFγ (γ-secretase-generated carboxyl-terminal fragment). Does not affect the formation of amyloid-β-precursor protein (APP).
产品信息 
Peptide Sequence  Z-Ile-Leu-CHO 
Form  White solid 
Primary Target  Aβ40 in vitro 
Primary Target IC50  7.9 µM 
Secondary target  blocking γ-secretase activity in vitro (Aβ40 IC50 = 7.9 µM; Aβ42 IC50 = 7.6 µM) and in cultured CHO 2b-7 cells that stably overexpress APP695 (Aβ40 IC50 = 11.5 µM; Aβ42 IC50 = 8.3 µM) 
Protect from Light  是的 
Packaged under inert gas  是的 
Cell permeable  是的 
Reversible  是的 
Purity  ≥95% by HPLC 
Chemical formula  C20H30N2O4 
Storage  -20°C 
Ship  Ambient Temperature Only
Standard Handling 

保存条件: -20°C
说明书地址: 点击查看详细
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