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Quercetagetin
3,3′,4′,5,6,7-Hexahydroxyflavone
A cell-permeable flavanol compound that acts a potent, ATP-competitive, and reversible inhibitor of PIM1 kinase (IC50 = 340 nM). Exhibits ≥7-fold selectivity over 8 other kinases tested, including PIM2 (IC50 = 3.45 µM), and little activity toward c-Abl even at concentrations as high as 200 µM. Inhibits cellular BAD phosphorylation (IC50 = 5.5 µM) and induces growth arrest (ED50 = 3.8 µM) in PIM1-expressing RWPE2 cells.
产品信息
Form Green solid
Molar mass 318.3
Protect from Light 是的
Packaged under inert gas 是的
Purity ≥95% by HPLC
Solubility DMSO
Chemical formula C15H10O8
CAS number 90-18-6
商店和运输信息
Hazardous Materials Attention: Due to the nature of the Hazardous Materials in this shipment, additional shipping chargesmay be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
Storage +2°C to +8°C
Ship Ambient Temperature Only
Toxic & Carcinogenic / Teratogenic |