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产品信息
A cell-permeable, irreversible, broad-spectrum caspase inhibitor (IC50 = 50, 100, 430, and <25 nM for caspase-1,-8, -9, and -3, respectively) with effective antiapoptotic properties against all major caspase-mediated cellular apoptosis pathways. Exhibits no cytotoxic effects even at extremely high concentrations. Shown to reduce ischemic brain damage and stroke-induced programmed cell death in thymus and spleen.
Form Liquid
Formulation Supplied as a 10 mM (1 mg/195 µl) solution in DMSO.
Primary Target caspase-1
Primary Target IC50 50 nM
Secondary target caspase-8 (IC50 = 100 nM), caspase-9 (IC50 = 430 nM)
Protect from Light 是的
Hygrocopic 是的
Packaged under inert gas 是的
Cell permeable 是的
Purity ≥90% by HPLC
Chemical formula C26H25F2N3O6
Storage -20°C |