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产品说明
A cell-permeable methyl ester derivative of Pepstatin A (Cat. No. 516481) that acts as a potent, non-competitive, transition-state analog inhibitor of γ-secretase (Kis = 150 nM, Kii = 320 nM in solubilized human γ-secretase at 20°C; Kis is the inhibition constant for inhibitor binding to the free enzyme and Kii is the inhibition constant for inhibitor binding to the Enzyme-Substrate complex). Sta = (3S,4S)-4-Amino-3-hydroxy-6-methyl-heptanoic acid.
产品信息
Form Lyophilized
Primary Target γ-secretase
Secondary target Kii = 320 nM, Kis = 150 nM
Packaged under inert gas 是的
Cell permeable 是的
Purity ≥95% by HPLC
Chemical formula C35H65N5O9
Storage -20°C
Ship Blue Ice Only
Standard Handling |