产品信息 CAS number 170905-75-6 Storage -20°C Form Off-white solid Primary Target MMP-1 Primary Target Ki 0.2 nM Secondary target Ki = 500 nM for MMP-2; Ki = 20 µM for MMP-3; Ki = 100 nM for MMP-8; and Ki = 100 nM for MMP-9 Purity ≥95% by HPLC Chemical formula C27H33N3O4 A potent broad-range inhibitor of matrix metalloproteinases (MMPs). Inhibits MMPs in vitro (Ki = 0.2 nM for MMP-1; Ki = 500 nM for MMP-2; Ki = 20 µM for MMP-3; Ki = 100 nM for MMP-8; and Ki = 100 nM for MMP-9). Also reduces the inflammatory and the hyperproliferative responses that occur following topical phorbol ester application.
