GGTI-2147 A cell-permeable non-thiol peptidomimetic that acts as a potent and selective inhibitor of geranylgeranyltransferase I (GGTase I). Blocks the geranyl-geranylation of Rap1A with an IC50 value that is over 60-fold lower than that required to disrupt the farnesylation of H-Ras (IC50 = 500 nM for Rap1A versus IC50 > 30 µM for H-Ras). 产品信息 Form Off-white solid Primary Target GGTase-I Secondary target Rap 1A (IC50 = 500 nM) Molar mass 470.6 Hygrocopic 是的 Packaged under inert gas 是的 Cell permeable 是的 Purity ≥95% by HPLC Solubility DMSO Chemical formula C28H30N4O3 CAS number 191102-87-1 商店和运输信息 Storage -20°C Ship Ambient Temperature Only Standard Handling