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产品信息：
Form Yellow solid
Primary Target DNA-PK
Primary Target IC50 270 nM
Secondary target IC50 = 32 µM, 3.7 µM, 22 µM and ~100 µM for α, β, &delta and γ, respectively
Protect from Light 是的
Packaged under inert gas 是的
Purity ≥95% by HPLC
Chemical formula C17H17NO3
CAS number 404009-46-7
Storage +2°C to +8°C
Ship Ambient Temperature Only
Carcinogenic / Teratogenic
产品信息：
A morpholino-benzophenone compound that acts as a potent, selective, reversible, and ATP-competitive inhibitor of DNA-PK (IC50 = 270 nM). Inhibits PI 3-K catalytic subunit p110-isozymes at higher concentrations (IC50 = 32 µM, 3.7 µM, 22 µM and ~ 100 µM for α, β, δ and γ, respectively) and weakly inhibits a panel of several other kinases, including, ATM, ATR, CK2, GRK2, mTOR, PI 3KC2α, PI 3KC2β, PI 3KC2γ and PI 4Kβ, even at concentrations as high as 50 µM. |