产品信息: Form Bright Yellow solid Primary Target DNA-PK activity Primary Target IC50 15 µM Protect from Light 是的 Packaged under inert gas 是的 Cell permeable 是的 Purity ≥90% by GC Chemical formula C9H9NO5 CAS number 20357-25-9 Storage +2°C to +8°C Ship Ambient Temperature Only Carcinogenic / Teratogenic 产品说明: A cell-permeable vanillin derivative that acts as a potent and selective inhibitor of DNA-PK (DNA-dependent protein kinase) activity (IC50 = 15 µM) and DNA-PK-mediated DSB (double strand break) DNA repair by NHEJ (non-homologous DNA-end-joining). Shown to effectively sensitize cells to killing by Cisplatin (Cat. No. 232120). Does not affect PKC or Chk2 kinase activities.