CATHEPSIN B, HUMAN LIVER

Cathepsin B, Human Liver
Native cathepsin B from human liver, purified by affinity chromatography. The most investigated enzyme of all lysosomal cysteine proteases. Upregulation and secretion of cathepsin B have been shown to occur in many types of tumors and to correlate positively with their invasive and metastatic capabilities. Cathepsin B is shown to facilitate tumor invasion by dissolving extracellular barriers.
产品信息
Form  Liquid
Formulation  In 50 mM sodium acetate buffer, 1 mM EDTA, pH 5.0.
Molar mass  27500
Avoid freeze/thaw  是的
Specific activity  ≥50 U/mg protein
Unit definition  One unit is defined as the amount of enzyme that will hydrolyze 1.0 µmol Z-RR-βNA per min at 40°C, pH 6.0 in the presence of DTT.
Purity  >95% by SDS-PAGE
Source  Prepared from tissue of individuals that have been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
pH value  optimum 3.5 - 6.0
EC number  3.4.22.1
CAS number  9047-22-7
Merck USA index 14, 1905
商店和运输信息
Storage  ≤ -70°C
Ship  Dry Ice Only
Standard Handling