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Cathepsin B, Human Liver
Native cathepsin B from human liver, purified by affinity chromatography and HPLC. The most investigated enzyme of all lysosomal cysteine proteases. Upregulation and secretion of cathepsin B have been shown to occur in many types of tumors and to correlate positively with their invasive and metastatic capabilities. Cathepsin B is shown to facilitate tumor invasion by dissolving extracellular barriers.
产品信息
Form Liquid
Formulation In 50 mM sodium acetate buffer, 1 mM EDTA, pH 5.0.
Molar mass 27500
Avoid freeze/thaw 是的
Specific activity ≥10 units/mg protein
Unit definition One unit is defined as the amount of enzyme that will hydrolyze 1.0 µmol Z-RR-β-naphthylamide per min at 40°C, using 100 mM Na+/K+ pH 6.0, with 1.33 mM EDTA and 2 mM DTT as the activation buffer.
Purity ≥95% by SDS-PAGE
Source Prepared from tissues of individuals that have been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
EC number 3.4.22.1
CAS number 9047-22-7
Merck USA index 14, 1905
商店和运输信息
Storage ≤ -70°C
Ship Dry Ice Only
Standard Handling |